Which HPV types are associated with the majority of cervical cancer cases?

The types of HPV most commonly linked to the majority of cervical cancer cases are HPV 16 and HPV 18. These are classified as high-risk HPV types due to their strong association with oncogenic potential, leading to the development of cervical intraepithelial neoplasia (CIN) and subsequently invasive cervical cancer.

HPV 16 and 18 account for a significant percentage of cervical cancer diagnoses globally. Evidence supports that persistent infection with these high-risk types is a crucial factor in the carcinogenic process, making them critical targets for cervical cancer prevention strategies, including vaccination and screening.

Although other types of HPV, such as 31 and 33, are also categorized as high-risk and can contribute to cervical cancer, they do not have the same predominant role as HPV 16 and 18. This is why recognizing these two types is essential in understanding the etiology of cervical cancer and formulating public health interventions.