Which age range is most commonly associated with Yolk Sac Tumor?

Yolk sac tumors, also known as endodermal sinus tumors, are germ cell tumors that are most commonly associated with children and young adults. The age range of 0-3 years is particularly significant because this is when yolk sac tumors are most frequently diagnosed, often presenting in the pediatric population. These tumors can also occur in older individuals but are relatively rare outside of this early age range. The distinct histological features of yolk sac tumors, such as the presence of Schiller-Duval bodies and alpha-fetoprotein production, underscore their origin from primordial germ cells, which are prevalent in younger patients. Therefore, identifying the age range of 0-3 years as the most common association with these tumors aligns with the clinical patterns seen in their diagnosis and presentation.