Which age group is most commonly affected by Burkitt Lymphoma?

Burkitt Lymphoma predominantly affects young children, particularly those in the age range of 5 to 10 years. This aggressive form of non-Hodgkin lymphoma is characterized by rapid growth and is associated with genetic alterations, notably translocations involving the MYC oncogene.

The occurrence of Burkitt Lymphoma in young children is linked to several factors, including the prevalence of Epstein-Barr virus (EBV) in certain geographic regions, which has been implicated in its pathogenesis. The lymphoma is categorized into three main types: endemic (often seen in Africa), sporadic (common in developed countries), and immunodeficiency-associated (occurs in individuals with weakened immune systems).

This lymphoma type is much less common in older age groups or adults. While teenagers and young adults can develop Burkitt Lymphoma, it is significantly rarer compared to its incidence in young children. Therefore, the age group most commonly affected aligns with pediatric cases, which is why young children is the correct answer.