What type of lesions are characteristic of Kaposi Sarcoma?

Kaposi Sarcoma is characterized by red-purple macules, papules, or nodules that typically appear on the lower extremities, particularly on the legs and feet. These lesions can also develop on other parts of the body, including the face, oral cavity, and internal organs, but their distinct color and appearance set them apart. The lesions arise due to the proliferation of endothelial cells, leading to vascular tumors that can be associated with the human herpesvirus 8 (HHV-8). It's this specific manifestation of red-purple macules that distinguishes Kaposi Sarcoma from other skin lesions.

The other options describe lesions that are more typical of different dermatological conditions. For instance, pearly papules on the face are indicative of basal cell carcinoma, while hyperpigmented plaques on the trunk are commonly associated with conditions such as dermatofibromas or other benign tumors. Blisters and pustules on the skin may represent infectious processes or inflammatory skin diseases, which are unrelated to Kaposi Sarcoma. Understanding the specific characteristics of Kaposi Sarcoma is crucial for accurate diagnosis and differentiation from other skin lesions.