What is the primary feature of Multiple Myeloma?

Multiple Myeloma is primarily characterized by the proliferation of plasma cells. Plasma cells are a specialized type of white blood cell that produce antibodies, and in Multiple Myeloma, these cells become malignant and start to multiply uncontrollably in the bone marrow. This leads to a range of complications, including disrupted blood cell production, bone lesions, and abnormal protein production, which can be identified through specific tests. The increase in these abnormal plasma cells is the hallmark of the disease and is crucial for diagnosis. Elevated levels of monoclonal immunoglobulin, known as M protein, are often detected in patients, further confirming the proliferation of plasma cells. Hence, recognizing plasma cell proliferation is essential for understanding the pathology of Multiple Myeloma.