What is the primary characteristic of Squamous Cell Carcinoma of the vagina?

The primary characteristic of Squamous Cell Carcinoma of the vagina is that it is often an extension from adjacent structures, such as the cervix or vulva. This cancer can develop as a result of the direct spread of malignant cells from these areas.

In many cases, patients may have a history of cervical intraepithelial neoplasia (CIN) or cervical cancer, and the vaginal carcinoma can frequently be linked to these conditions. This is important because it implies that awareness and screening for cervical issues can effectively aid in early detection of squamous cell carcinoma if it arises in the vagina.

Other characteristics do not accurately reflect the nature of this type of cancer. For instance, while there are benign conditions affecting the vagina, squamous cell carcinoma itself is malignant, making it inaccurate to describe it as mostly benign. Additionally, instead of being rare in women over 50, squamous cell carcinoma tends to occur more frequently in older women, especially those who may have had prior gynecological malignancies. Lastly, dietary habits are not a primary factor related to the development of this form of cancer, as the primary risk factors are more closely associated with HPV infection and local extension from nearby lesions.