What is a notable presentation of Paget's disease?

Paget's disease of the breast is characterized by specific skin changes associated with underlying breast carcinoma. The notable presentation includes an eczematoid lesion of the nipple or areola, which often manifests as an itchy, scaly, or crusty area. This condition typically arises due to the infiltration of malignant cells that extend from the ducts of the breast to the surface of the nipple, leading to these distinctive dermatological changes.

The eczematoid appearance is specifically important because it can be an initial sign of the disease, prompting further investigation for an underlying malignancy. It is essential for healthcare providers to recognize this presentation, as the changes might appear benign but are often indicative of more serious pathologies.

Other options, while they may relate to breast conditions, do not capture the classic presentation of Paget's disease specifically. For example, ulcerated skin on the breast can occur in various contexts, including inflammatory breast cancer, but is not specific to Paget's disease. Similarly, fibroadenoma formation pertains to a benign condition, and necrosis of breast tissue would be associated with other forms of breast pathology, such as infarction rather than Paget's disease itself.