What is a hallmark of xanthogranulomatous pyelonephritis?

Xanthogranulomatous pyelonephritis is characterized by the presence of golden yellow nodules, which are rich in lipid-laden macrophages. This condition is a form of chronic kidney infection and inflammation that leads to the destruction of kidney tissue, resulting in the accumulation of these yellowish nodules in the renal parenchyma. The golden yellow color is a distinguishing feature of the disease, primarily due to the presence of lipid-laden foam cells that give it its characteristic appearance.

Other features associated with xanthogranulomatous pyelonephritis may include inflammatory changes and necrosis, but the defining hallmark that sets it apart from other renal pathologies is indeed the presence of these golden yellow nodules. This characteristic helps pathologists identify the condition during examination of kidney tissue samples.