What is a common cause of Curling Ulcer?

Curling ulcers are a specific type of stress-related mucosal disease that refer to gastric ulcers that occur following severe physical stress. They are most commonly observed in patients who have experienced acute severe burns. The pathogenesis behind Curling ulcers is thought to involve the extensive physiological stress associated with severe burns, which can lead to decreased blood flow to the gastric mucosa and result in mucosal ischemia. This ischemia can cause mucosal injury and the formation of ulcers.

In contrast, while chronic liver disease and elevated intracranial pressure can contribute to gastrointestinal complications, they do not specifically lead to Curling ulcers as acute severe burns do. Genetic factors play a role in many diseases, but they are not a common or direct cause of Curling ulcers. Thus, acute severe burns stand out as the principal cause of this particular ulcer type due to the stress response triggered by extensive injury.