What is a characteristic feature of Crohn's disease?

A characteristic feature of Crohn's disease is the presence of skip lesions and a cobblestone appearance. Skip lesions refer to the patchy areas of inflammation that can occur throughout the gastrointestinal tract, meaning that some sections of the intestine may be affected while others remain normal. This contrasts with diseases like ulcerative colitis, which typically presents with continuous inflammation.

The cobblestone appearance is a result of the deep ulcers and fissures that occur in the intestinal mucosa, giving the surface a rugged, uneven texture. This distinct morphology is a hallmark of Crohn's disease and helps differentiate it from other inflammatory bowel diseases. The ability to affect any part of the gastrointestinal tract, from the mouth to the anus, is also central to understanding Crohn's disease.

Overall, the identification of skip lesions and cobblestone appearance is vital for diagnosis and management, making it an important characteristic feature of Crohn's disease.