What condition is associated with precocious puberty in young girls and features ovarian masses?

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Granulosa cell tumors are a type of sex-cord stromal tumor of the ovary that can produce estrogens, leading to a condition known as precocious puberty when they occur in young girls. These tumors can be unilateral or bilateral and often present as solid or cystic masses within the ovaries. The excess estrogen produced can stimulate the development of secondary sexual characteristics at an unusually early age, which is the hallmark of precocious puberty.

In addition to the early onset of puberty, the presence of ovarian masses is a distinguishing feature of granulosa cell tumors. The diagnosis is typically confirmed through imaging studies and histological examination, where the characteristic features of the tumor can be identified.

Other options do not primarily involve precocious puberty associated with ovarian masses:

  • Sheehan syndrome is a condition resulting from pituitary gland failure due to severe blood loss during or after childbirth, which does not involve ovarian masses or precocious puberty.
  • Eclampsia is a complication of pregnancy characterized by seizures, and it does not relate to ovarian conditions or precocious puberty.
  • Clear cell tumors can occur in the ovary but are more commonly associated with adult-type ovarian cancers and may not specifically lead to precocious puberty.

Thus, the association of granul

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