What are the typical signs of hypothyroidism?

Hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones, typically presents with several characteristic signs and symptoms due to a slowed metabolism. The correct choice includes fatigue, cold intolerance, and weight gain, which are commonly associated with this condition.

Fatigue is prevalent in hypothyroidism because the body's metabolism slows down, leading to reduced energy levels and overwhelming feelings of tiredness. Cold intolerance occurs as the metabolic rate decreases, which impacts the body's ability to generate heat, causing individuals to feel excessively cold even in mild environments. Weight gain is another common sign, as the slowed metabolism leads to weight increase despite normal or reduced caloric intake, due to the body becoming less efficient at using energy.

The other options include symptoms that do not align with hypothyroidism. For example, weight loss and increased heart rate are typically seen in hyperthyroidism, where there is an excess of thyroid hormones. Increased sweating and heat intolerance relate to hyperthyroidism as well, reflecting an elevated metabolism. Lastly, a persistent cough and fever are nonspecific signs that do not indicate thyroid dysfunction and are more consistent with respiratory or infectious processes.