Intraductal papillary mucinous neoplasm of the pancreas is characterized by which feature?

Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is primarily characterized by the presence of mucinous cysts. IPMN arises from the pancreatic ductal epithelium and is distinguished by the accumulation of mucin, leading to cystic dilation of the ducts. The mucinous fluid is produced by neoplastic epithelial cells, which proliferate and can lead to intraductal cyst formation.

The mucinous nature of these cysts is a key diagnostic feature, as it sets IPMNs apart from other pancreatic lesions. IPMNs can present with various types of cysts based on the extent of the disease and the involvement of the main pancreatic duct or branches. This mucinous component is also linked to the potential for malignancy, but it does not imply that all cases are malignant at diagnosis; it suggests a risk of progression to invasive cancer over time.

Understanding the characteristics of IPMNs is essential for diagnosis and management, as they require careful monitoring due to their potential for transformation into more aggressive forms.