In what kind of emphysema do large blebs commonly form?

Paraseptal emphysema is characterized by the formation of large blebs, which are air-filled spaces that can develop in the peripheral areas of the lungs. This type of emphysema primarily affects the alveolar septa, leading to the destruction of the walls between alveoli. As the condition progresses, the absence of structural integrity allows for the formation of these blebs.

These blebs are more likely to occur in the subpleural region of the lungs, and their presence can increase the risk of pneumothorax, especially if these blebs rupture. Paraseptal emphysema is often associated with young adults and can be linked to factors such as smoking or genetic predispositions, though the exact cause can be multifactorial.

In contrast, other types of emphysema focus on different areas of the lung architecture and do not typically result in the formation of large blebs, making paraseptal emphysema distinct in this aspect.