In Kartagener Syndrome, which symptom is NOT typically associated?

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Kartagener Syndrome is a genetic disorder characterized by a triad of symptoms: chronic sinusitis, bronchiectasis, and situs inversus. This condition arises due to issues with ciliary function in the respiratory tract, leading to recurrent respiratory infections and chronic respiratory conditions.

In this context, chronic sinusitis occurs because the impaired cilia are less effective at clearing mucus and pathogens from the sinus cavities, resulting in ongoing inflammation and infection. Bronchiectasis, on the other hand, develops due to the repeated cycles of infection and inflammation, causing the bronchial tubes to become permanently dilated and damaged. Bronchial obstruction may also be seen due to mucus accumulation and structural changes in the airways, contributing further to respiratory symptoms.

The association of autism spectrum disorder with Kartagener Syndrome is not established and is therefore not a symptom typically associated with this condition. Autism spectrum disorders arise from a complex interplay of genetic and environmental factors that do not have a direct connection to the primary respiratory and anatomical manifestations seen in Kartagener Syndrome.

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